Difference between revisions of "YIR002C"
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| − | '''Description of YIR002C:''' Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype<ref name='S000042465'>Scheller J, et al. (2000) MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage. Genetics 155(3):1069-81 {{SGDpaper|S000042465}} PMID 10880470</ref><ref name='S000076156'>Schurer KA, et al. (2004) Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics 166(4):1673-86 {{SGDpaper|S000076156}} PMID 15126389 | + | '''Description of YIR002C:''' Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype<ref name='S000129182'>Kang YH, et al. (2009) The MPH1 Gene of Saccharomyces cerevisiae Functions in Okazaki Fragment Processing. J Biol Chem 284(16):10376-86 {{SGDpaper|S000129182}} PMID 19181670</ref><ref name='S000042465'>Scheller J, et al. (2000) MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage. Genetics 155(3):1069-81 {{SGDpaper|S000042465}} PMID 10880470</ref><ref name='S000076156'>Schurer KA, et al. (2004) Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics 166(4):1673-86 |
| − | + | {{SGDpaper|S000076156}} PMID 15126389</ref> | |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YIR002C |
| Gene name | MPH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:360393..357412 |
| Primary SGDID | S000001441 |
Description of YIR002C: Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype[1][2][3]
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References
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- ↑ Kang YH, et al. (2009) The MPH1 Gene of Saccharomyces cerevisiae Functions in Okazaki Fragment Processing. J Biol Chem 284(16):10376-86 SGD PMID 19181670
- ↑ Scheller J, et al. (2000) MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage. Genetics 155(3):1069-81 SGD PMID 10880470
- ↑ Schurer KA, et al. (2004) Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics 166(4):1673-86 SGD PMID 15126389
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