Difference between revisions of "YER100W"
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| − | '''Description of YER100W:''' Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway<ref name=' | + | '''Description of YER100W:''' Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway<ref name='S000057852'>Biederer T, et al. (1996) Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J 15(9):2069-76 {{SGDpaper|S000057852}} PMID 8641272</ref><ref name='S000053643'>Gilon T, et al. (2000) Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair. Mol Cell Biol 20(19):7214-9 {{SGDpaper|S000053643}} PMID 10982838</ref><ref name='S000052708'>Sommer T and Jentsch S (1993) A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature 365(6442):176-9 {{SGDpaper|S000052708}} PMID 8396728</ref><ref name='S000074588'>Walter J, et al. (2001) Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J 20(12):3124-31 |
{{SGDpaper|S000074588}} PMID 11406589</ref> | {{SGDpaper|S000074588}} PMID 11406589</ref> | ||
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Revision as of 13:05, 25 February 2010
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| Systematic name | YER100W |
| Gene name | UBC6 |
| Aliases | DOA2 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:359558..360310 |
| Primary SGDID | S000000902 |
Description of YER100W: Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway[1][2][3][4]
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References
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- ↑ Biederer T, et al. (1996) Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J 15(9):2069-76 SGD PMID 8641272
- ↑ Gilon T, et al. (2000) Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair. Mol Cell Biol 20(19):7214-9 SGD PMID 10982838
- ↑ Sommer T and Jentsch S (1993) A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature 365(6442):176-9 SGD PMID 8396728
- ↑ Walter J, et al. (2001) Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J 20(12):3124-31 SGD PMID 11406589
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