Difference between revisions of "YLR397C"
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| − | '''Description of YLR397C:''' ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs<ref name='S000048059'>Thorsness PE, et al. (1993) AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPases. Yeast 9(11):1267-71 {{SGDpaper|S000048059}} PMID 8109176</ref><ref name='S000070262'>Zakalskiy A, et al. (2002) Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization. J Biol Chem 277(30):26788-95 | + | '''Description of YLR397C:''' ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; may be involved in degradation of aberrant mRNAs<ref name='S000048059'>Thorsness PE, et al. (1993) AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPases. Yeast 9(11):1267-71 {{SGDpaper|S000048059}} PMID 8109176</ref><ref name='S000070262'>Zakalskiy A, et al. (2002) Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization. J Biol Chem 277(30):26788-95 {{SGDpaper|S000070262}} PMID 12006565</ref><ref name='S000123602'>Pertschy B, et al. (2007) Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1. Mol Cell Biol 27(19):6581-92 |
| − | {{SGDpaper| | + | {{SGDpaper|S000123602}} PMID 17646390</ref> |
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Revision as of 13:05, 11 December 2009
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| Systematic name | YLR397C |
| Gene name | AFG2 |
| Aliases | DRG1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:914892..912550 |
| Primary SGDID | S000004389 |
Description of YLR397C: ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; may be involved in degradation of aberrant mRNAs[1][2][3]
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References
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- ↑ Thorsness PE, et al. (1993) AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPases. Yeast 9(11):1267-71 SGD PMID 8109176
- ↑ Zakalskiy A, et al. (2002) Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization. J Biol Chem 277(30):26788-95 SGD PMID 12006565
- ↑ Pertschy B, et al. (2007) Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1. Mol Cell Biol 27(19):6581-92 SGD PMID 17646390
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