Difference between revisions of "YKL166C"
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| − | '''Description of YKL166C:''' cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway | + | '''Description of YKL166C:''' cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase<ref name='S000042132'>Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 {{SGDpaper|S000042132}} PMID 3036373</ref><ref name='S000042460'>Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 {{SGDpaper|S000042460}} PMID 8641464</ref><ref name='S000043708'>Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 {{SGDpaper|S000043708}} PMID 3037314</ref><ref name='S000131843'>Tudisca V, et al. (2009) Differential localization to cytoplasm, nucleus or P-bodies of yeast PKA subunits under different growth conditions. Eur J Cell Biol |
| − | {{SGDpaper| | + | {{SGDpaper|S000131843}} PMID 19804918</ref> |
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Revision as of 13:05, 30 November 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKL166C |
| Gene name | TPK3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:135710..134514 |
| Primary SGDID | S000001649 |
Description of YKL166C: cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase[1][2][3][4]
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Community Commentary
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Interactions
Genetic
Strain Background: S288C, W303 (see detailed notes from Rodney Rothstein and Stephan Bartsch for the W303 strain used in the study), industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]
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References
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- ↑ Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
- ↑ Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
- ↑ Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
- ↑ Tudisca V, et al. (2009) Differential localization to cytoplasm, nucleus or P-bodies of yeast PKA subunits under different growth conditions. Eur J Cell Biol SGD PMID 19804918
- ↑ Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
- ↑ submitted by Kevin J Verstrepen on 2004-03-11
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References
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See Help:Categories on how to add the wiki page for this gene to a Category </protect>
