Difference between revisions of "YLR139C"
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+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Genetic ==== | ||
+ | [[Category:Topic:Interactions:Genetic]] | ||
+ | YLR139C is a suppressor of MTF2 [[Category:Genetic Interaction with MTF2]] | ||
+ | |||
+ | '''Strain Background''': DBY2006<br> | ||
+ | '''Genotype''': ACB1<br> | ||
+ | '''Mutation type(s)''': null | ||
+ | |||
+ | The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Genetic ==== | ||
+ | [[Category:Topic:Interactions:Genetic]] | ||
+ | YLR139C is a suppressor of MTF2 [[Category:Genetic Interaction with MTF2]] | ||
+ | |||
+ | |||
+ | '''Strain Background''': DBY2006<br> | ||
+ | '''Genotype''': ACB1<br> | ||
+ | '''Mutation type(s)''': null | ||
+ | |||
+ | The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
+ | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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{{RefHelp}} | {{RefHelp}} |
Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YLR139C | |
Gene name | SLS1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr XII:423474..421543 | |
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Description of YLR139C: Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV; coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery[1][2][3]
Interactions
Genetic
YLR139C is a suppressor of MTF2
Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [2] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
YLR139C is a suppressor of MTF2
Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [2] [4]
References
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- ↑ Rodeheffer MS and Shadel GS (2003) Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem 278(20):18695-701 SGD PMID 12637560
- ↑ 2.0 2.1 2.2 Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 SGD PMID 11805046
- ↑ Rouillard JM, et al. (1996) SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion. Mol Gen Genet 252(6):700-8 SGD PMID 8917313
- ↑ 4.0 4.1 submitted by Gerald Shadel on 2003-06-05
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