Difference between revisions of "YOL002C"
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| − | '''Description of YOL002C:''' Plasma membrane protein involved in zinc | + | '''Description of YOL002C:''' Plasma membrane protein involved in zinc homeostasis and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc<ref name='S000076221'>Lyons TJ, et al. (2004) Metalloregulation of yeast membrane steroid receptor homologs. Proc Natl Acad Sci U S A 101(15):5506-11 {{SGDpaper|S000076221}} PMID 15060275</ref><ref name='S000069897'>Karpichev IV, et al. (2002) Multiple regulatory roles of a novel Saccharomyces cerevisiae protein, encoded by YOL002c, in lipid and phosphate metabolism. J Biol Chem 277(22):19609-17 {{SGDpaper|S000069897}} PMID 11916977</ref><ref name='S000080492'>Narasimhan ML, et al. (2005) Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. Mol Cell 17(2):171-80 |
{{SGDpaper|S000080492}} PMID 15664187</ref> | {{SGDpaper|S000080492}} PMID 15664187</ref> | ||
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Revision as of 02:00, 25 August 2009
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| Systematic name | YOL002C |
| Gene name | IZH2 |
| Aliases | PHO36 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:324365..323412 |
| Primary SGDID | S000005362 |
Description of YOL002C: Plasma membrane protein involved in zinc homeostasis and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc[1][2][3]
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References
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- ↑ Lyons TJ, et al. (2004) Metalloregulation of yeast membrane steroid receptor homologs. Proc Natl Acad Sci U S A 101(15):5506-11 SGD PMID 15060275
- ↑ Karpichev IV, et al. (2002) Multiple regulatory roles of a novel Saccharomyces cerevisiae protein, encoded by YOL002c, in lipid and phosphate metabolism. J Biol Chem 277(22):19609-17 SGD PMID 11916977
- ↑ Narasimhan ML, et al. (2005) Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. Mol Cell 17(2):171-80 SGD PMID 15664187
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