Difference between revisions of "YDR120C"
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| − | '''Description of YDR120C:''' tRNA methyltransferase | + | '''Description of YDR120C:''' tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments<ref name='S000041042'>Ellis SR, et al. (1989) Amino-terminal extension generated from an upstream AUG codon increases the efficiency of mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferases. Mol Cell Biol 9(4):1611-20 {{SGDpaper|S000041042}} PMID 2657400</ref><ref name='S000052056'>Ellis SR, et al. (1986) Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J Biol Chem 261(21):9703-9 {{SGDpaper|S000052056}} PMID 2426253</ref><ref name='S000052812'>Rose AM, et al. (1992) Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Mol Cell Biol 12(12):5652-8 |
{{SGDpaper|S000052812}} PMID 1448094</ref> | {{SGDpaper|S000052812}} PMID 1448094</ref> | ||
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Revision as of 13:05, 20 July 2009
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| Systematic name | YDR120C |
| Gene name | TRM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:693259..691547 |
| Primary SGDID | S000002527 |
Description of YDR120C: tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments[1][2][3]
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References
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- ↑ Ellis SR, et al. (1989) Amino-terminal extension generated from an upstream AUG codon increases the efficiency of mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferases. Mol Cell Biol 9(4):1611-20 SGD PMID 2657400
- ↑ Ellis SR, et al. (1986) Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J Biol Chem 261(21):9703-9 SGD PMID 2426253
- ↑ Rose AM, et al. (1992) Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Mol Cell Biol 12(12):5652-8 SGD PMID 1448094
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