Difference between revisions of "YDL175C"

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'''Description of YDL175C:''' RING finger protein that interacts with the arginine methyltransferase Hmt1p; may regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air1p<ref name='S000059204'>Inoue K, et al. (2000) Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p. J Biol Chem 275(42):32793-9
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'''Description of YDL175C:''' zinc knuckle protein, involved in nuclear RNA quality control as a component of the TRAMP complex; stimulates the poly(A)polymerase activity of Pap2p in vitro; functionally redundant with Air1p<ref name='S000059204'>Inoue K, et al. (2000) Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p. J Biol Chem 275(42):32793-9 {{SGDpaper|S000059204}} PMID 10896665</ref><ref name='S000081438'>Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 {{SGDpaper|S000081438}} PMID 15828860</ref><ref name='S000081843'>LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 {{SGDpaper|S000081843}} PMID 15935758</ref><ref name='S000081864'>Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37
  {{SGDpaper|S000059204}} PMID 10896665</ref>
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  {{SGDpaper|S000081864}} PMID 15935759</ref>
 
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Revision as of 13:05, 1 June 2009

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Systematic name YDL175C
Gene name AIR2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:145519..144485
Primary SGDID S000002334


Description of YDL175C: zinc knuckle protein, involved in nuclear RNA quality control as a component of the TRAMP complex; stimulates the poly(A)polymerase activity of Pap2p in vitro; functionally redundant with Air1p[1][2][3][4]




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References

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  1. Inoue K, et al. (2000) Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p. J Biol Chem 275(42):32793-9 SGD PMID 10896665
  2. Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
  3. LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
  4. Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 SGD PMID 15935759

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