Difference between revisions of "YDR432W"
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| − | '''Description of YDR432W:''' RNA-binding protein that carries poly(A) | + | '''Description of YDR432W:''' RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; required for pre-mRNA splicing; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm<ref name='S000039584'>Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46 {{SGDpaper|S000039584}} PMID 8675010</ref><ref name='S000059966'>Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 {{SGDpaper|S000059966}} PMID 11233987</ref><ref name='S000080250'>Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 {{SGDpaper|S000080250}} PMID 15542855</ref><ref name='S000128599'>Kress TL, et al. (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34 {{SGDpaper|S000128599}} PMID 19061647</ref><ref name='S000127827'>Dermody JL, et al. (2008) Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation. PLoS ONE 3(9):e3273 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127827}} PMID 18818768</ref> |
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Revision as of 13:05, 24 April 2009
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| Systematic name | YDR432W |
| Gene name | NPL3 |
| Aliases | MTR13, MTS1, NAB1, NOP3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1328776..1330020 |
| Primary SGDID | S000002840 |
Description of YDR432W: RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; required for pre-mRNA splicing; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm[1][2][3][4][5]
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References
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- ↑ Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46 SGD PMID 8675010
- ↑ Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 SGD PMID 11233987
- ↑ Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 SGD PMID 15542855
- ↑ Kress TL, et al. (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34 SGD PMID 19061647
- ↑ Dermody JL, et al. (2008) Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation. PLoS ONE 3(9):e3273 SGD PMID 18818768
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