Difference between revisions of "YNL123W"
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| − | '''Description of YNL123W:''' Serine protease and general molecular chaperone; involved in response to heat stress; may contribute to lipid homeostasis | + | '''Description of YNL123W:''' Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases<ref name='S000114563'>Fahrenkrog B, et al. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci 117(Pt 1):115-26 {{SGDpaper|S000114563}} PMID 14657274</ref><ref name='S000114909'>Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 {{SGDpaper|S000114909}} PMID 16608876</ref><ref name='S000114421'>Tong F, et al. (2006) Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. Mol Genet Genomics 275(4):330-43 {{SGDpaper|S000114421}} PMID 16470384</ref><ref name='S000128102'>Padmanabhan N, et al. (2009) The Yeast HtrA Orthologue Ynm3 Is a Protease with Chaperone Activity that Aids Survival Under Heat Stress. Mol Biol Cell 20(1):68-77 |
{{SGDpaper|S000128102}} PMID 18946088</ref> | {{SGDpaper|S000128102}} PMID 18946088</ref> | ||
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Revision as of 13:05, 9 April 2009
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| Systematic name | YNL123W |
| Gene name | NMA111 |
| Aliases | YNM3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:394687..397680 |
| Primary SGDID | S000005067 |
Description of YNL123W: Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases[1][2][3][4]
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References
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- ↑ Fahrenkrog B, et al. (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci 117(Pt 1):115-26 SGD PMID 14657274
- ↑ Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 SGD PMID 16608876
- ↑ Tong F, et al. (2006) Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. Mol Genet Genomics 275(4):330-43 SGD PMID 16470384
- ↑ Padmanabhan N, et al. (2009) The Yeast HtrA Orthologue Ynm3 Is a Protease with Chaperone Activity that Aids Survival Under Heat Stress. Mol Biol Cell 20(1):68-77 SGD PMID 18946088
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