Difference between revisions of "YOR127W"

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'''Description of YOR127W:''' GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth<ref name='S000072335'>Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80 {{SGDpaper|S000072335}} PMID 12455995</ref><ref name='S000053458'>Stevenson BJ, et al. (1995) Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes Dev 9(23):2949-63
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'''Description of YOR127W:''' GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth<ref name='S000053458'>Stevenson BJ, et al. (1995) Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes Dev 9(23):2949-63 {{SGDpaper|S000053458}} PMID 7498791</ref><ref name='S000072335'>Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80
  {{SGDpaper|S000053458}} PMID 7498791</ref>
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  {{SGDpaper|S000072335}} PMID 12455995</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YOR127W
Gene name RGA1
Aliases DBM1, THE1
Feature type ORF, Verified
Coordinates Chr XV:561171..564194
Primary SGDID S000005653


Description of YOR127W: GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Stevenson BJ, et al. (1995) Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes Dev 9(23):2949-63 SGD PMID 7498791
  2. Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80 SGD PMID 12455995
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

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