Difference between revisions of "YMR023C"
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| − | '''Description of YMR023C:''' Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3<ref name='S000080941'>Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 {{SGDpaper|S000080941}} PMID 15509579</ref><ref name='S000071798'>Li X and Guan MX (2002) A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol Cell Biol 22(21):7701-11 {{SGDpaper|S000071798}} PMID 12370316 | + | '''Description of YMR023C:''' Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3<ref name='S000044773'>Decoster E, et al. (1993) MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase. J Mol Biol 232(1):79-88 {{SGDpaper|S000044773}} PMID 8392589</ref><ref name='S000053827'>Colby G, et al. (1998) MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem 273(43):27945-52 {{SGDpaper|S000053827}} PMID 9774408</ref><ref name='S000080941'>Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 {{SGDpaper|S000080941}} PMID 15509579</ref><ref name='S000071798'>Li X and Guan MX (2002) A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol Cell Biol 22(21):7701-11 |
| − | + | {{SGDpaper|S000071798}} PMID 12370316</ref> | |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YMR023C |
| Gene name | MSS1 |
| Aliases | PET53 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:321016..319436 |
| Primary SGDID | S000004625 |
Description of YMR023C: Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3[1][2][3][4]
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References
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- ↑ Decoster E, et al. (1993) MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase. J Mol Biol 232(1):79-88 SGD PMID 8392589
- ↑ Colby G, et al. (1998) MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem 273(43):27945-52 SGD PMID 9774408
- ↑ Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 SGD PMID 15509579
- ↑ Li X and Guan MX (2002) A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol Cell Biol 22(21):7701-11 SGD PMID 12370316
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