Difference between revisions of "YLR347C"
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| − | '''Description of YLR347C:''' Karyopherin beta, forms a complex with Srp1p/Kap60p; mediates nuclear import of cargo proteins via a nuclear localization signal; involved in PC biosynthesis; interacts with nucleoporins to guide transport across the nuclear pore comple<ref name=' | + | '''Description of YLR347C:''' Karyopherin beta, forms a complex with Srp1p/Kap60p; mediates nuclear import of cargo proteins via a nuclear localization signal; involved in PC biosynthesis; interacts with nucleoporins to guide transport across the nuclear pore comple<ref name='S000046571'>Enenkel C, et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270(28):16499-502 {{SGDpaper|S000046571}} PMID 7622450</ref><ref name='S000049555'>Aitchison JD, et al. (1996) Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274(5287):624-7 {{SGDpaper|S000049555}} PMID 8849456</ref><ref name='S000074600'>Gilchrist D and Rexach M (2003) Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm. J Biol Chem 278(51):51937-49 {{SGDpaper|S000074600}} PMID 14514698</ref><ref name='S000128919'>Mackinnon MA, et al. (2009) The kap60-kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J Biol Chem 284(11):7376-84 |
| − | {{SGDpaper| | + | {{SGDpaper|S000128919}} PMID 19141610</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YLR347C |
| Gene name | KAP95 |
| Aliases | RSL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:826412..823827 |
| Primary SGDID | S000004339 |
Description of YLR347C: Karyopherin beta, forms a complex with Srp1p/Kap60p; mediates nuclear import of cargo proteins via a nuclear localization signal; involved in PC biosynthesis; interacts with nucleoporins to guide transport across the nuclear pore comple[1][2][3][4]
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References
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- ↑ Enenkel C, et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270(28):16499-502 SGD PMID 7622450
- ↑ Aitchison JD, et al. (1996) Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274(5287):624-7 SGD PMID 8849456
- ↑ Gilchrist D and Rexach M (2003) Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm. J Biol Chem 278(51):51937-49 SGD PMID 14514698
- ↑ Mackinnon MA, et al. (2009) The kap60-kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J Biol Chem 284(11):7376-84 SGD PMID 19141610
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