Difference between revisions of "YLR043C"

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'''Description of YLR043C:''' Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance<ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000069486'>Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 {{SGDpaper|S000069486}} PMID 11929546</ref><ref name='S000057828'>Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 {{SGDpaper|S000057828}} PMID 8603912</ref><ref name='S000052969'>Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 {{SGDpaper|S000052969}} PMID 9813082</ref><ref name='S000051462'>Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 {{SGDpaper|S000051462}} PMID 9382859</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 {{SGDpaper|S000048402}} PMID 9015301</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73
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'''Description of YLR043C:''' Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance<ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 {{SGDpaper|S000047291}} PMID 10037727</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 {{SGDpaper|S000048402}} PMID 9015301</ref><ref name='S000051462'>Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 {{SGDpaper|S000051462}} PMID 9382859</ref><ref name='S000052969'>Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 {{SGDpaper|S000052969}} PMID 9813082</ref><ref name='S000057828'>Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 {{SGDpaper|S000057828}} PMID 8603912</ref><ref name='S000069486'>Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 {{SGDpaper|S000069486}} PMID 11929546</ref><ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78
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  {{SGDpaper|S000071764}} PMID 12410842</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YLR043C
Gene name TRX1
Aliases LMA1
Feature type ORF, Verified
Coordinates Chr XII:232014..231703
Primary SGDID S000004033


Description of YLR043C: Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance[1][2][3][4][5][6][7]




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References

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  1. Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 SGD PMID 10037727
  2. Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301
  3. Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 SGD PMID 9382859
  4. Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 SGD PMID 9813082
  5. Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 SGD PMID 8603912
  6. Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 SGD PMID 11929546
  7. Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 SGD PMID 12410842

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