Difference between revisions of "YGR231C"
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| − | '''Description of YGR231C:''' Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation<ref name=' | + | '''Description of YGR231C:''' Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation<ref name='S000045872'>Coates PJ, et al. (1997) The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr Biol 7(8):607-10 {{SGDpaper|S000045872}} PMID 9259555</ref><ref name='S000050840'>Berger KH and Yaffe MP (1998) Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Mol Cell Biol 18(7):4043-52 {{SGDpaper|S000050840}} PMID 9632789</ref><ref name='S000050987'>Nijtmans LG, et al. (2000) Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins. EMBO J 19(11):2444-51 {{SGDpaper|S000050987}} PMID 10835343</ref><ref name='S000080623'>Tatsuta T, et al. (2005) Formation of membrane-bound ring complexes by prohibitins in mitochondria. Mol Biol Cell 16(1):248-59 {{SGDpaper|S000080623}} PMID 15525670</ref><ref name='S000073674'>Piper PW, et al. (2002) The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell 1(2):149-57 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073674}} PMID 12882345</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YGR231C |
| Gene name | PHB2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:953483..952551 |
| Primary SGDID | S000003463 |
Description of YGR231C: Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation[1][2][3][4][5]
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References
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- ↑ Coates PJ, et al. (1997) The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr Biol 7(8):607-10 SGD PMID 9259555
- ↑ Berger KH and Yaffe MP (1998) Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Mol Cell Biol 18(7):4043-52 SGD PMID 9632789
- ↑ Nijtmans LG, et al. (2000) Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins. EMBO J 19(11):2444-51 SGD PMID 10835343
- ↑ Tatsuta T, et al. (2005) Formation of membrane-bound ring complexes by prohibitins in mitochondria. Mol Biol Cell 16(1):248-59 SGD PMID 15525670
- ↑ Piper PW, et al. (2002) The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell 1(2):149-57 SGD PMID 12882345
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