Difference between revisions of "YGL086W"

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'''Description of YGL086W:''' Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p<ref name='S000057390'>Hardwick KG and Murray AW (1995) Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131(3):709-20 {{SGDpaper|S000057390}} PMID 7593191</ref><ref name='S000047902'>Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6
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'''Description of YGL086W:''' Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p<ref name='S000047902'>Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 {{SGDpaper|S000047902}} PMID 8688079</ref><ref name='S000057390'>Hardwick KG and Murray AW (1995) Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131(3):709-20
  {{SGDpaper|S000047902}} PMID 8688079</ref>
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  {{SGDpaper|S000057390}} PMID 7593191</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YGL086W
Gene name MAD1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:347122..349371
Primary SGDID S000003054


Description of YGL086W: Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p[1][2]




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References

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  1. Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 SGD PMID 8688079
  2. Hardwick KG and Murray AW (1995) Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131(3):709-20 SGD PMID 7593191

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