Difference between revisions of "YDR263C"

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'''Description of YDR263C:''' Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination<ref name='S000073928'>Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 {{SGDpaper|S000073928}} PMID 12827502</ref><ref name='S000045102'>Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 {{SGDpaper|S000045102}} PMID 10628970</ref><ref name='S000043383'>Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 {{SGDpaper|S000043383}} PMID 9079876</ref><ref name='S000041233'>Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83
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'''Description of YDR263C:''' Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination<ref name='S000041233'>Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83 {{SGDpaper|S000041233}} PMID 9628902</ref><ref name='S000043383'>Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 {{SGDpaper|S000043383}} PMID 9079876</ref><ref name='S000045102'>Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 {{SGDpaper|S000045102}} PMID 10628970</ref><ref name='S000073928'>Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9
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  {{SGDpaper|S000073928}} PMID 12827502</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YDR263C
Gene name DIN7
Aliases DIN3
Feature type ORF, Verified
Coordinates Chr IV:995531..994239
Primary SGDID S000002671


Description of YDR263C: Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination[1][2][3][4]




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References

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  1. Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83 SGD PMID 9628902
  2. Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 SGD PMID 9079876
  3. Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 SGD PMID 10628970
  4. Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 SGD PMID 12827502

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