Difference between revisions of "YDL128W"

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'''Description of YDL128W:''' Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter<ref name='S000046399'>Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 {{SGDpaper|S000046399}} PMID 8628289</ref><ref name='S000046126'>Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6 {{SGDpaper|S000046126}} PMID 10371152</ref><ref name='S000041805'>Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41
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'''Description of YDL128W:''' Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter<ref name='S000041805'>Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41 {{SGDpaper|S000041805}} PMID 8668190</ref><ref name='S000046399'>Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 {{SGDpaper|S000046399}} PMID 8628289</ref><ref name='S000046126'>Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6
{{SGDpaper|S000041805}} PMID 8668190</ref>
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{{SGDpaper|S000046126}} PMID 10371152</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YDL128W
Gene name VCX1
Aliases HUM1, MNR1
Feature type ORF, Verified
Coordinates Chr IV:232652..233887
Primary SGDID S000002286


Description of YDL128W: Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter[1][2][3]




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References

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  1. Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41 SGD PMID 8668190
  2. Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 SGD PMID 8628289
  3. Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6 SGD PMID 10371152

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