Difference between revisions of "YIL046W"
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| − | '''Description of YIL046W:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name=' | + | '''Description of YIL046W:''' F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus<ref name='S000042750'>Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 {{SGDpaper|S000042750}} PMID 10637232</ref><ref name='S000059458'>Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 |
| − | {{SGDpaper| | + | {{SGDpaper|S000059458}} PMID 11027256</ref> |
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Revision as of 13:05, 31 March 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YIL046W |
| Gene name | MET30 |
| Aliases | ZRG11 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:268650..270572 |
| Primary SGDID | S000001308 |
Description of YIL046W: F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus[1][2]
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Community Commentary
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Interactions
Other Interactions
Other Topic: NOT Regulatory
Other Interactions interaction with SWE1
Despite previous reports to the contrary, Met30p is not required for Swe1p degradation [3] [4]
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References
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- ↑ Rouillon A, et al. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J 19(2):282-94 SGD PMID 10637232
- ↑ Smothers DB, et al. (2000) The abundance of Met30p limits SCF(Met30p) complex activity and is regulated by methionine availability. Mol Cell Biol 20(21):7845-52 SGD PMID 11027256
- ↑ McMillan JN, et al. (2002) Determinants of Swe1p degradation in Saccharomyces cerevisiae. Mol Biol Cell 13(10):3560-75 SGD PMID 12388757
- ↑ submitted by Daniel Lew on 2003-03-03
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