Difference between revisions of "YCL008C"
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| − | '''Description of YCL008C:''' Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype<ref name=' | + | '''Description of YCL008C:''' Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype<ref name='S000060251'>Babst M, et al. (2000) Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1(3):248-58 {{SGDpaper|S000060251}} PMID 11208108</ref><ref name='S000061300'>Katzmann DJ, et al. (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106(2):145-55 |
| − | {{SGDpaper| | + | {{SGDpaper|S000061300}} PMID 11511343</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YCL008C |
| Gene name | STP22 |
| Aliases | VPS23 |
| Feature type | ORF, Verified |
| Coordinates | Chr III:106853..105696 |
| Primary SGDID | S000000514 |
Description of YCL008C: Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype[1][2]
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References
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- ↑ Babst M, et al. (2000) Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1(3):248-58 SGD PMID 11208108
- ↑ Katzmann DJ, et al. (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106(2):145-55 SGD PMID 11511343
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