Difference between revisions of "YOL051W"

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'''Description of YOL051W:''' Component of the Mediator complex; interacts with RNA polymerase II and the general transcription factors to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors<ref name='S000075930'>Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69():729-49 {{SGDpaper|S000075930}} PMID 10966474</ref><ref name='S000073244'>Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 {{SGDpaper|S000073244}} PMID 12715155</ref><ref name='S000068888'>Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6
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'''Description of YOL051W:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors<ref name='S000075930'>Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69:729-49 {{SGDpaper|S000075930}} PMID 10966474</ref><ref name='S000073244'>Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 {{SGDpaper|S000073244}} PMID 12715155</ref><ref name='S000068888'>Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6 {{SGDpaper|S000068888}} PMID 11470794</ref><ref name='S000057341'>Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8
  {{SGDpaper|S000068888}} PMID 11470794</ref>
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  {{SGDpaper|S000057341}} PMID 7479899</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YOL051W
Gene name GAL11
Aliases ABE1, MED15, RAR3, SDS4, SPT13
Feature type ORF, Verified
Coordinates Chr XV:234939..238184
Primary SGDID S000005411


Description of YOL051W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors[1][2][3][4]




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References

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  1. Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69:729-49 SGD PMID 10966474
  2. Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 SGD PMID 12715155
  3. Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6 SGD PMID 11470794
  4. Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8 SGD PMID 7479899

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