Difference between revisions of "YGR206W"
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| − | '''Description of YGR206W:''' ESCRT-I subunit | + | '''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 {{SGDpaper|S000123193}} PMID 17145965</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 |
{{SGDpaper|S000071347}} PMID 12140549</ref> | {{SGDpaper|S000071347}} PMID 12140549</ref> | ||
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Revision as of 06:21, 26 February 2009
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| Systematic name | YGR206W |
| Gene name | MVB12 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:910437..910742 |
| Primary SGDID | S000003438 |
Description of YGR206W: ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin[1][2][3][4][5]
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References
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- ↑ Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 SGD PMID 17145965
- ↑ Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 SGD PMID 17135292
- ↑ Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 SGD PMID 15883373
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
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