Difference between revisions of "YDR432W"

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'''Description of YDR432W:''' RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; required for the splicing of pre-mRNAs; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm<ref name='S000039584'>Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46 {{SGDpaper|S000039584}} PMID 8675010</ref><ref name='S000059966'>Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 {{SGDpaper|S000059966}} PMID 11233987</ref><ref name='S000080250'>Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 {{SGDpaper|S000080250}} PMID 15542855</ref><ref name='S000128599'>Kress TL, et al. (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34
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'''Description of YDR432W:''' RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; required for the splicing of pre-mRNAs; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm<ref name='S000128599'>Kress TL, et al. (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34 {{SGDpaper|S000128599}} PMID 19061647</ref><ref name='S000080250'>Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 {{SGDpaper|S000080250}} PMID 15542855</ref><ref name='S000059966'>Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 {{SGDpaper|S000059966}} PMID 11233987</ref><ref name='S000039584'>Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46
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Revision as of 13:05, 16 January 2009

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Systematic name YDR432W
Gene name NPL3
Aliases MTR13, MTS1, NAB1, NOP3
Feature type ORF, Verified
Coordinates Chr IV:1328776..1330020
Primary SGDID S000002840


Description of YDR432W: RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; required for the splicing of pre-mRNAs; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm[1][2][3][4]




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References

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  1. Kress TL, et al. (2008) A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast. Mol Cell 32(5):727-34 SGD PMID 19061647
  2. Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 SGD PMID 15542855
  3. Gilbert W, et al. (2001) Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. RNA 7(2):302-13 SGD PMID 11233987
  4. Lee MS, et al. (1996) A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev 10(10):1233-46 SGD PMID 8675010

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