Difference between revisions of "YBR248C"
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| − | '''Description of YBR248C:''' Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor<ref name=' | + | '''Description of YBR248C:''' Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor<ref name='S000057959'>Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 {{SGDpaper|S000057959}} PMID 8852895</ref><ref name='S000055916'>Kuenzler M, et al. (1993) Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae. J Bacteriol 175(17):5548-58 {{SGDpaper|S000055916}} PMID 8366040</ref><ref name='S000044976'>Chittur SV, et al. (2000) Expression and purification of imidazole glycerol phosphate synthase from Saccharomyces cerevisiae. Protein Expr Purif 18(3):366-77 |
| − | {{SGDpaper| | + | {{SGDpaper|S000044976}} PMID 10733892</ref> |
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Revision as of 13:05, 16 January 2009
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| Systematic name | YBR248C |
| Gene name | HIS7 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:716460..714802 |
| Primary SGDID | S000000452 |
Description of YBR248C: Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor[1][2][3]
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References
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- ↑ Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
- ↑ Kuenzler M, et al. (1993) Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae. J Bacteriol 175(17):5548-58 SGD PMID 8366040
- ↑ Chittur SV, et al. (2000) Expression and purification of imidazole glycerol phosphate synthase from Saccharomyces cerevisiae. Protein Expr Purif 18(3):366-77 SGD PMID 10733892
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