Difference between revisions of "YGL235W"

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'''Description of YGL235W:''' Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2<ref name='S000125271'>Chamilos G, et al. (2008) Genomewide Screening for Genes Associated with Gliotoxin Resistance and Sensitivity in Saccharomyces cerevisiae. Antimicrob Agents Chemother 52(4):1325-9 {{SGDpaper|S000125271}} PMID 18212113</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
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'''Description of YGL235W:''' Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000125271'>Chamilos G, et al. (2008) Genomewide Screening for Genes Associated with Gliotoxin Resistance and Sensitivity in Saccharomyces cerevisiae. Antimicrob Agents Chemother 52(4):1325-9
  {{SGDpaper|S000074306}} PMID 14574415</ref>
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  {{SGDpaper|S000125271}} PMID 18212113</ref>
 
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Revision as of 03:15, 19 December 2008

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Systematic name YGL235W
Gene name
Aliases
Feature type ORF, Uncharacterized
Coordinates Chr VII:55279..55815
Primary SGDID S000003204


Description of YGL235W: Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [3]





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References

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  1. 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  2. Chamilos G, et al. (2008) Genomewide Screening for Genes Associated with Gliotoxin Resistance and Sensitivity in Saccharomyces cerevisiae. Antimicrob Agents Chemother 52(4):1325-9 SGD PMID 18212113
  3. submitted by Jeff Ubersax on 2004-01-27

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