Difference between revisions of "YGL037C"
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| − | '''Description of YGL037C:''' Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span<ref name=' | + | '''Description of YGL037C:''' Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span<ref name='S000069212'>Ghislain M, et al. (2002) Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1. Yeast 19(3):215-24 {{SGDpaper|S000069212}} PMID 11816029</ref><ref name='S000073098'>Anderson RM, et al. (2003) Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936):181-5 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073098}} PMID 12736687</ref> |
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Revision as of 03:15, 19 December 2008
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| Systematic name | YGL037C |
| Gene name | PNC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:427953..427303 |
| Primary SGDID | S000003005 |
Description of YGL037C: Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span[1][2]
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References
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- ↑ Ghislain M, et al. (2002) Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1. Yeast 19(3):215-24 SGD PMID 11816029
- ↑ Anderson RM, et al. (2003) Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936):181-5 SGD PMID 12736687
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