Difference between revisions of "YDR419W"
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| − | '''Description of YDR419W:''' DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins<ref name=' | + | '''Description of YDR419W:''' DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins<ref name='S000046956'>Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 {{SGDpaper|S000046956}} PMID 9974380</ref><ref name='S000051688'>Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 {{SGDpaper|S000051688}} PMID 10713149</ref><ref name='S000070428'>Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 {{SGDpaper|S000070428}} PMID 12154119</ref><ref name='S000075149'>Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 |
| − | {{SGDpaper| | + | {{SGDpaper|S000075149}} PMID 14585988</ref> |
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Revision as of 03:15, 19 December 2008
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| Systematic name | YDR419W |
| Gene name | RAD30 |
| Aliases | DBH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1303167..1305065 |
| Primary SGDID | S000002827 |
Description of YDR419W: DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins[1][2][3][4]
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References
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- ↑ Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 SGD PMID 9974380
- ↑ Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 SGD PMID 10713149
- ↑ Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 SGD PMID 12154119
- ↑ Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 SGD PMID 14585988
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