Difference between revisions of "YAL023C"
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| − | '''Description of YAL023C:''' Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals | + | '''Description of YAL023C:''' Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals<ref name='S000049666'>Lussier M, et al. (1995) Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity. J Biol Chem 270(6):2770-5 {{SGDpaper|S000049666}} PMID 7852348</ref><ref name='S000072926'>Girrbach V and Strahl S (2003) Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem 278(14):12554-62 |
| − | {{SGDpaper| | + | {{SGDpaper|S000072926}} PMID 12551906</ref> |
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Revision as of 03:40, 18 December 2008
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| Systematic name | YAL023C |
| Gene name | PMT2 |
| Aliases | FUN25 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:108552..106273 |
| Primary SGDID | S000000021 |
Description of YAL023C: Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals[1][2]
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References
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- ↑ Lussier M, et al. (1995) Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity. J Biol Chem 270(6):2770-5 SGD PMID 7852348
- ↑ Girrbach V and Strahl S (2003) Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem 278(14):12554-62 SGD PMID 12551906
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