Difference between revisions of "YCL044C"
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− | '''Description of YCL044C:''' Subunit | + | '''Description of YCL044C:''' Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA<ref name='S000127993'>Dunn CD, et al. (2008) Mgr3p and Mgr1p Are Adaptors for the Mitochondrial i-AAA Protease Complex. Mol Biol Cell {{SGDpaper|S000127993}} PMID 18843051</ref><ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 |
{{SGDpaper|S000113568}} PMID 16267274</ref> | {{SGDpaper|S000113568}} PMID 16267274</ref> | ||
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Revision as of 14:05, 13 October 2008
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Systematic name | YCL044C |
Gene name | MGR1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr III:48364..47111 |
Primary SGDID | S000000549 |
Description of YCL044C: Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA[1][2]
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References
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- ↑ Dunn CD, et al. (2008) Mgr3p and Mgr1p Are Adaptors for the Mitochondrial i-AAA Protease Complex. Mol Biol Cell SGD PMID 18843051
- ↑ Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
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