Difference between revisions of "YFR031C"
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| − | '''Description of YFR031C:''' Component of the condensin complex | + | '''Description of YFR031C:''' Component of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus<ref name='S000127505'>Haeusler RA, et al. (2008) Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes. Genes Dev 22(16):2204-14 {{SGDpaper|S000127505}} PMID 18708579</ref><ref name='S000073810'>Stray JE and Lindsley JE (2003) Biochemical analysis of the yeast condensin Smc2/4 complex: an ATPase that promotes knotting of circular DNA. J Biol Chem 278(28):26238-48 {{SGDpaper|S000073810}} PMID 12719426</ref><ref name='S000046263'>Strunnikov AV, et al. (1995) SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev 9(5):587-99 |
{{SGDpaper|S000046263}} PMID 7698648</ref> | {{SGDpaper|S000046263}} PMID 7698648</ref> | ||
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Revision as of 13:05, 30 September 2008
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| Systematic name | YFR031C |
| Gene name | SMC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:220094..216582 |
| Primary SGDID | S000001927 |
Description of YFR031C: Component of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus[1][2][3]
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References
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- ↑ Haeusler RA, et al. (2008) Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes. Genes Dev 22(16):2204-14 SGD PMID 18708579
- ↑ Stray JE and Lindsley JE (2003) Biochemical analysis of the yeast condensin Smc2/4 complex: an ATPase that promotes knotting of circular DNA. J Biol Chem 278(28):26238-48 SGD PMID 12719426
- ↑ Strunnikov AV, et al. (1995) SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev 9(5):587-99 SGD PMID 7698648
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