Difference between revisions of "YKL052C"
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| − | '''Description of YKL052C:''' Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases<ref name='S000114260'>Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 {{SGDpaper|S000114260}} PMID 16415853</ref><ref name=' | + | '''Description of YKL052C:''' Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases<ref name='S000114260'>Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 {{SGDpaper|S000114260}} PMID 16415853</ref><ref name='S000080667'>Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 {{SGDpaper|S000080667}} PMID 15664196</ref><ref name='S000080444'>Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 {{SGDpaper|S000080444}} PMID 15640796</ref><ref name='S000072943'>Li Y and Elledge SJ (2003) The DASH complex component Ask1 is a cell cycle-regulated Cdk substrate in Saccharomyces cerevisiae. Cell Cycle 2(2):143-8 {{SGDpaper|S000072943}} PMID 12695666</ref><ref name='S000069052'>Li Y, et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16(2):183-97 |
{{SGDpaper|S000069052}} PMID 11799062</ref> | {{SGDpaper|S000069052}} PMID 11799062</ref> | ||
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Revision as of 13:05, 14 July 2008
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| Systematic name | YKL052C |
| Gene name | ASK1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:340190..339312 |
| Primary SGDID | S000001535 |
Description of YKL052C: Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases[1][2][3][4][5]
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References
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- ↑ Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 SGD PMID 16415853
- ↑ Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 SGD PMID 15664196
- ↑ Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 SGD PMID 15640796
- ↑ Li Y and Elledge SJ (2003) The DASH complex component Ask1 is a cell cycle-regulated Cdk substrate in Saccharomyces cerevisiae. Cell Cycle 2(2):143-8 SGD PMID 12695666
- ↑ Li Y, et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16(2):183-97 SGD PMID 11799062
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