Difference between revisions of "YIL042C"
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| − | '''Description of YIL042C:''' Mitochondrial kinase, | + | '''Description of YIL042C:''' Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p<ref name='S000125220'>Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem {{SGDpaper|S000125220}} PMID 18180296</ref><ref name='S000115275'>Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 |
{{SGDpaper|S000115275}} PMID 16643908</ref> | {{SGDpaper|S000115275}} PMID 16643908</ref> | ||
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Revision as of 13:05, 21 March 2008
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| Systematic name | YIL042C |
| Gene name | PKP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:276291..275107 |
| Primary SGDID | S000001304 |
Description of YIL042C: Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p[1][2]
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References
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- ↑ Gey U, et al. (2008) Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases. J Biol Chem SGD PMID 18180296
- ↑ Krause-Buchholz U, et al. (2006) YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex. FEBS Lett 580(11):2553-60 SGD PMID 16643908
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