Difference between revisions of "YGR063C"

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'''Description of YGR063C:''' Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing<ref name='S000073348'>SGD (2007) Information without a citation in SGD  {{SGDpaper|S000073348}} PMID </ref><ref name='S000072823'>Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 {{SGDpaper|S000072823}} PMID 12554661</ref><ref name='S000072734'>Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 {{SGDpaper|S000072734}} PMID 12556496</ref><ref name='S000059512'>Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91
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'''Description of YGR063C:''' Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing<ref name='S000059512'>Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91 {{SGDpaper|S000059512}} PMID 11173517</ref><ref name='S000072734'>Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 {{SGDpaper|S000072734}} PMID 12556496</ref><ref name='S000072823'>Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 {{SGDpaper|S000072823}} PMID 12554661</ref><ref name='S000073348'>SGD (2007) Information without a citation in SGD 
  {{SGDpaper|S000059512}} PMID 11173517</ref>
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  {{SGDpaper|S000073348}} PMID </ref>
 
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Revision as of 03:15, 19 December 2008

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Systematic name YGR063C
Gene name SPT4
Aliases
Feature type ORF, Verified
Coordinates Chr VII:617828..617520
Primary SGDID S000003295


Description of YGR063C: Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing[1][2][3][4]




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References

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  1. Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91 SGD PMID 11173517
  2. Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 SGD PMID 12556496
  3. Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 SGD PMID 12554661
  4. SGD (2007) Information without a citation in SGD SGD PMID

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