Difference between revisions of "YPL203W"

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=== Interactions ===
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
  
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'''Strain Background''': S288C, W303, industrial<br>
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Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating
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ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. <ref name='S000075255'>Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 {{SGDpaper|S000075255}} PMID 14654433</ref> <ref name = 'CAset9888-2004-03-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9888 Kevin J Verstrepen] on 2004-03-11</ref>
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==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
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'''Strain Background''': S288C, W303, industrial<br>
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Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating
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ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. <ref name='S000075255'>Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 {{SGDpaper|S000075255}} PMID 14654433</ref> <ref name = 'CAset9888-2004-03-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9888 Kevin J Verstrepen] on 2004-03-11</ref>
  
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==References==
 
==References==
 
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Revision as of 16:05, 23 January 2007

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Systematic name YPL203W
Gene name TPK2
Aliases PKA2, PKA3, YKR1
Feature type ORF, Verified
Coordinates Chr XVI:166255..167397
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Description of YPL203W: Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; activates filamentous growth[1][2][3][4]



Interactions

Genetic

Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating

ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]


Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Genetic

Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating

ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]


References

See Help:References on how to add references

  1. Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87 SGD PMID 10373537
  2. Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
  3. Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
  4. Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
  5. 5.0 5.1 Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
  6. 6.0 6.1 submitted by Kevin J Verstrepen on 2004-03-11

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