Difference between revisions of "YOR026W"

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==Community Commentary==
 
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==References==
 
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Revision as of 07:18, 30 January 2007

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Systematic name YOR026W
Gene name BUB3
Aliases
Feature type ORF, Verified
Coordinates Chr XV:379781..380806


Description of YOR026W: Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p[1][2][3][4]




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Community Commentary

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References

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  1. Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 SGD PMID 11726501
  2. Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439
  3. Brady DM and Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11):675-8 SGD PMID 10837255
  4. Martinez-Exposito MJ, et al. (1999) Retention of the BUB3 checkpoint protein on lagging chromosomes. Proc Natl Acad Sci U S A 96(15):8493-8 SGD PMID 10411903

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