Difference between revisions of "YDR085C"
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| − | '''Description of YDR085C:''' Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p<ref name='S000122697'>Changwei Z, et al. (2007) Afr1p has a role in regulating the localization of Mpk1p at the shmoo tip in Saccharomyces cerevisiae. FEBS Lett () {{SGDpaper|S000122697}} PMID 17509572</ref><ref name='S000051757'>Giot L and Konopka JB (1997) Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis. Mol Biol Cell 8(6):987-98 {{SGDpaper|S000051757}} PMID 9201710</ref><ref name='S000041075'>Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13(11):6876-88 {{SGDpaper|S000041075}} PMID 8413281</ref><ref name='S000039269'>DeMattei CR, et al. (2000) Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics 155(1):43-55 | + | '''Description of YDR085C:''' Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p<ref name='S000122697'>Changwei Z, et al. (2007) Afr1p has a role in regulating the localization of Mpk1p at the shmoo tip in Saccharomyces cerevisiae. FEBS Lett 581(14):2670-4 {{SGDpaper|S000122697}} PMID 17509572</ref><ref name='S000051757'>Giot L and Konopka JB (1997) Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis. Mol Biol Cell 8(6):987-98 {{SGDpaper|S000051757}} PMID 9201710</ref><ref name='S000041075'>Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13(11):6876-88 {{SGDpaper|S000041075}} PMID 8413281</ref><ref name='S000039269'>DeMattei CR, et al. (2000) Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics 155(1):43-55 |
{{SGDpaper|S000039269}} PMID 10790383</ref> | {{SGDpaper|S000039269}} PMID 10790383</ref> | ||
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Revision as of 13:05, 9 June 2007
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| Systematic name | YDR085C |
| Gene name | AFR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:616147..614285 |
| Primary SGDID | S000002492 |
Description of YDR085C: Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p[1][2][3][4]
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References
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- ↑ Changwei Z, et al. (2007) Afr1p has a role in regulating the localization of Mpk1p at the shmoo tip in Saccharomyces cerevisiae. FEBS Lett 581(14):2670-4 SGD PMID 17509572
- ↑ Giot L and Konopka JB (1997) Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis. Mol Biol Cell 8(6):987-98 SGD PMID 9201710
- ↑ Konopka JB (1993) AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol 13(11):6876-88 SGD PMID 8413281
- ↑ DeMattei CR, et al. (2000) Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics 155(1):43-55 SGD PMID 10790383
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