Difference between revisions of "YDL003W"
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− | + | Mcd1 also involves in hydrogen peroxide-induced apoptosis. Upon induction of cell death, Mcd1 is cleaved and the C-terminal fragment is translocated from nucleus into mitochondria, causing the decrease of mitochondrial membrane potential and the amplification of cell death in a cytochrome c-dependent manner. | |
+ | MBC 19(5):2127-34,2008 | ||
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==References== | ==References== | ||
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Revision as of 10:20, 29 April 2008
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Systematic name | YDL003W |
Gene name | MCD1 |
Aliases | PDS3, RHC21, SCC1 |
Feature type | ORF, Verified |
Coordinates | Chr IV:444680..446380 |
Primary SGDID | S000002161 |
Description of YDL003W: Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase[1]
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Contents
Community Commentary
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Mcd1 also involves in hydrogen peroxide-induced apoptosis. Upon induction of cell death, Mcd1 is cleaved and the C-terminal fragment is translocated from nucleus into mitochondria, causing the decrease of mitochondrial membrane potential and the amplification of cell death in a cytochrome c-dependent manner. MBC 19(5):2127-34,2008
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References
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