Difference between revisions of "YFR044C"
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| − | '''Description of YFR044C:''' | + | '''Description of YFR044C:''' Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)<ref name='S000120080'>Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 {{SGDpaper|S000120080}} PMID 17179087</ref><ref name='S000129858'>Kaur H, et al. (2009) Dug1p is a Cys-Gly peptidase of the gamma -glutamyl cycle of Saccharomyces cerevisiae, and represents a novel family of Cys-Gly peptidases. J Biol Chem |
| − | {{SGDpaper| | + | {{SGDpaper|S000129858}} PMID 19346245</ref> |
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Revision as of 14:05, 14 April 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFR044C |
| Gene name | DUG1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:241424..239979 |
| Primary SGDID | S000001940 |
Description of YFR044C: Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)[1][2]
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Community Commentary
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [3] [4]
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References
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- Jump up ↑ Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 SGD PMID 17179087
- Jump up ↑ Kaur H, et al. (2009) Dug1p is a Cys-Gly peptidase of the gamma -glutamyl cycle of Saccharomyces cerevisiae, and represents a novel family of Cys-Gly peptidases. J Biol Chem SGD PMID 19346245
- Jump up ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- Jump up ↑ submitted by Steffen Ohlmeier on 2004-04-08
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