Difference between revisions of "YHR087W"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001129 YHR087W] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001129 YHR087W] | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RTC3 '' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | ||
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| − | '''Description of YHR087W:''' Protein of unknown function involved in RNA metabolism; | + | '''Description of YHR087W:''' Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity<ref name='S000126069'>Addinall SG and Lydall D (2008) {{SGDpaper|S000126069}} PMID </ref><ref name='S000115063'>Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 {{SGDpaper|S000115063}} PMID 16529906</ref><ref name='S000080732'>Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 {{SGDpaper|S000080732}} PMID 15701634</ref><ref name='S000080728'>Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9 |
{{SGDpaper|S000080728}} PMID 15701631</ref> | {{SGDpaper|S000080728}} PMID 15701631</ref> | ||
<br> | <br> | ||
Revision as of 13:05, 16 April 2008
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| Systematic name | YHR087W |
| Gene name | RTC3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:280822..281157 |
| Primary SGDID | S000001129 |
Description of YHR087W: Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity[1][2][3][4]
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References
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- ↑ Addinall SG and Lydall D (2008) SGD PMID
- ↑ Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 SGD PMID 16529906
- ↑ Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 SGD PMID 15701634
- ↑ Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9 SGD PMID 15701631
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