Difference between revisions of "YLR442C"

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==Community Commentary==
 
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==References==
 
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Revision as of 07:18, 30 January 2007

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Systematic name YLR442C
Gene name SIR3
Aliases CMT1, MAR2, STE8
Feature type ORF, Verified
Coordinates Chr XII:1022248..1019312


Description of YLR442C: Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p[1][2][3]




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Community Commentary

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References

See Help:References on how to add references

  1. Moretti P and Shore D (2001) Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast. Mol Cell Biol 21(23):8082-94 SGD PMID 11689698
  2. Hecht A, et al. (1996) Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383(6595):92-6 SGD PMID 8779721
  3. Rine J and Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116(1):9-22 SGD PMID 3297920

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