Difference between revisions of "YIL121W"

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Revision as of 15:20, 21 May 2007

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Systematic name YIL121W
Gene name QDR2
Aliases
Feature type ORF, Verified
Coordinates Chr IX:132241..133869
Primary SGDID S000001383


Description of YIL121W: Multidrug transporter required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake; member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)[1][2][3]




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References

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  1. Vargas RC, et al. (2007) Saccharomyces cerevisiae Multidrug Resistance Transporter Qdr2 Is Implicated in Potassium Uptake, Providing a Physiological Advantage to Quinidine-Stressed Cells. Eukaryot Cell 6(2):134-42 SGD PMID 17189489
  2. Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 SGD PMID 15649438
  3. Vargas RC, et al. (2004) Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant. Antimicrob Agents Chemother 48(7):2531-7 SGD PMID 15215105

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