Difference between revisions of "YLR139C"

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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
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YLR139C is a suppressor of  MTF2 [[Category:Genetic Interaction with MTF2]]
  
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'''Strain Background''': DBY2006<br>
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'''Genotype''': ACB1<br>
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'''Mutation type(s)''': null
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The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref>
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==Community Commentary==
 
==Community Commentary==
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
 +
[[Category:Topic:Interactions:Genetic]]
 +
YLR139C is a suppressor of  MTF2 [[Category:Genetic Interaction with MTF2]]
 +
 +
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'''Strain Background''': DBY2006<br>
 +
'''Genotype''': ACB1<br>
 +
'''Mutation type(s)''': null
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The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref>
  
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==References==
 
==References==
 
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Revision as of 16:05, 23 January 2007

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Systematic name YLR139C
Gene name SLS1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:423474..421543
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Description of YLR139C: Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV; coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery[1][2][3]



Interactions

Genetic

YLR139C is a suppressor of MTF2


Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null

The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [2] [4]


Community Commentary

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Interactions

Genetic

YLR139C is a suppressor of MTF2


Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null

The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [2] [4]


References

See Help:References on how to add references

  1. Rodeheffer MS and Shadel GS (2003) Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem 278(20):18695-701 SGD PMID 12637560
  2. 2.0 2.1 2.2 Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 SGD PMID 11805046
  3. Rouillard JM, et al. (1996) SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion. Mol Gen Genet 252(6):700-8 SGD PMID 8917313
  4. 4.0 4.1 submitted by Gerald Shadel on 2003-06-05

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