Difference between revisions of "YKL197C"

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=== DNA and RNA Details ===
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==== Other DNA and RNA Details ====
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'''Other Topic''': expression [[Category:Topic:expression]]
  
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess. <ref name='S000073646'>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 {{SGDpaper|S000073646}} PMID 12414795</ref> <ref name = 'CAset9153-2003-07-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9153 Viktor Boer] on 2003-07-25</ref>
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=== Protein Details ===
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==== Other Protein Details ====
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'''Other Topic''': Homology [[Category:Topic:Homology]]
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Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. <ref name='S000114809'>Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 {{SGDpaper|S000114809}} PMID 16556314</ref> <ref name = 'CAset11335-2006-04-12'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=11335 Toni Gabaldon] on 2006-04-12</ref>
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==Community Commentary==
 
==Community Commentary==
 
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=== DNA and RNA Details ===
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[[Category:Topic:DNA and RNA Details]]
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==== Other DNA and RNA Details ====
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[[Category:Topic:DNA and RNA Details:Other DNA and RNA Details]]
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'''Other Topic''': expression [[Category:Topic:expression]]
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess. <ref name='S000073646'>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 {{SGDpaper|S000073646}} PMID 12414795</ref> <ref name = 'CAset9153-2003-07-25'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9153 Viktor Boer] on 2003-07-25</ref>
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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Other Protein Details ====
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[[Category:Topic:Protein Details:Other Protein Details]]
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'''Other Topic''': Homology [[Category:Topic:Homology]]
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Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. <ref name='S000114809'>Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 {{SGDpaper|S000114809}} PMID 16556314</ref> <ref name = 'CAset11335-2006-04-12'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=11335 Toni Gabaldon] on 2006-04-12</ref>
  
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==References==
 
==References==
 
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Revision as of 16:05, 23 January 2007

Share your knowledge...Edit this entry!

Systematic name YKL197C
Gene name PEX1
Aliases PAS1
Feature type ORF, Verified
Coordinates Chr XI:73870..70739
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Description of YKL197C: AAA-family ATPase peroxin required for peroxisome biogenesis, contains two 230 amino acid ATP-binding AAA cassettes, upregulated in anaerobiosis; Pex1p and Pex6p interact via their N-terminal AAA-cassettes[1][2][3][4]



DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [5] [6]


Protein Details

Other Protein Details

Other Topic: Homology

Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [7] [8]


Community Commentary

About Community Commentary. Please share your knowledge!

DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [5] [6]


Protein Details

Other Protein Details

Other Topic: Homology

Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [7] [8]


References

See Help:References on how to add references

  1. Birschmann I, et al. (2005) Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p. FEBS J 272(1):47-58 SGD PMID 15634331
  2. Skoneczny M and Rytka J (2000) Oxygen and haem regulate the synthesis of peroxisomal proteins: catalase A, acyl-CoA oxidase and Pex1p in the yeast Saccharomyces cerevisiae; the regulation of these proteins by oxygen is not mediated by haem. Biochem J 350 Pt 1():313-9 SGD PMID 10926859
  3. Erdmann R, et al. (1991) PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases. Cell 64(3):499-510 SGD PMID 1825027
  4. Krause T, et al. (1994) Effect of site-directed mutagenesis of conserved lysine residues upon Pas1 protein function in peroxisome biogenesis. Yeast 10(12):1613-20 SGD PMID 7725796
  5. 5.0 5.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. 6.0 6.1 submitted by Viktor Boer on 2003-07-25
  7. 7.0 7.1 Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
  8. 8.0 8.1 submitted by Toni Gabaldon on 2006-04-12

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