Difference between revisions of "YIR019C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
Line 23: Line 23:
 
<br>
 
<br>
 
<br>
 
<br>
 +
=== Alleles, Strains, and Phenotypes ===
 +
[[Category:Topic:Alleles, Strains, and Phenotypes]]
 +
==== Multiple Knockout Strains ====
 +
[[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]]
  
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4618<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], FLO11/MUC1 promoter substituted with S.p.Adh+ promoter [[Category:Phenotype:FLO11/MUC1 promoter substituted with S.p.Adh+ promoter]]
 +
 +
Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4469<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
 +
 +
Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4618<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], FLO11/MUC1 promoter substituted with S.p.Adh+ promoter [[Category:Phenotype:FLO11/MUC1 promoter substituted with S.p.Adh+ promoter]]
 +
 +
Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4469<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
 +
 +
Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
=== Alleles, Strains, and Phenotypes ===
 +
[[Category:Topic:Alleles, Strains, and Phenotypes]]
 +
==== Multiple Knockout Strains ====
 +
[[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]]
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4618<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], FLO11/MUC1 promoter substituted with S.p.Adh+ promoter [[Category:Phenotype:FLO11/MUC1 promoter substituted with S.p.Adh+ promoter]]
 +
 +
Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4469<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
 +
 +
Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4618<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], FLO11/MUC1 promoter substituted with S.p.Adh+ promoter [[Category:Phenotype:FLO11/MUC1 promoter substituted with S.p.Adh+ promoter]]
 +
 +
Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
'''Strain Background''': Sigma1278b (Sigma2000 series)<br>
 +
'''Genotype''': MCY4469<br>
 +
'''Together with''': REG1, SIP1, GAL83, SIP2<br>
 +
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
 +
 +
Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. <ref name='S000072732'>Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 {{SGDpaper|S000072732}} PMID 12556493</ref> <ref name = 'CAset6176-2003-03-27'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6176 Valmik K. Vyas] on 2003-03-27</ref>
  
 +
{{ShortCenteredHR}}
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}

Revision as of 17:05, 23 January 2007

Share your knowledge...Edit this entry!

Systematic name YIR019C
Gene name MUC1
Aliases FLO11, STA4
Feature type ORF, Verified
Coordinates Chr IX:393672..389569
Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs.


Description of YIR019C: GPI-anchored cell surface glycoprotein required for diploid pseudohyphal formation and haploid invasive growth, transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)[1][2][3]



Alleles, Strains, and Phenotypes

Multiple Knockout Strains

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4618
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null), FLO11/MUC1 promoter substituted with S.p.Adh+ promoter

Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4469
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)

Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4618
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null), FLO11/MUC1 promoter substituted with S.p.Adh+ promoter

Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4469
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)

Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. [4] [5]

Community Commentary

About Community Commentary. Please share your knowledge!

Alleles, Strains, and Phenotypes

Multiple Knockout Strains

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4618
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null), FLO11/MUC1 promoter substituted with S.p.Adh+ promoter

Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4469
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)

Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4618
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null), FLO11/MUC1 promoter substituted with S.p.Adh+ promoter

Deletion of REG1 in cells where FLO11/MUC1 expression is clamped (by substitution of the FLO11 promoter with the S.pombe Adh+promoter) causes an increase in invasion. [4] [5]

Strain Background: Sigma1278b (Sigma2000 series)
Genotype: MCY4469
Together with: REG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)

Deletion of FLO11/MUC1 suppresses reg1's constitutive invasion phenotype, but not its constitutive filamentous phenotype. [4] [5]

References

See Help:References on how to add references

  1. Jump up ↑ Guo B, et al. (2000) A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Proc Natl Acad Sci U S A 97(22):12158-63 SGD PMID 11027318
  2. Jump up ↑ Lambrechts MG, et al. (1996) Muc1, a mucin-like protein that is regulated by Mss10, is critical for pseudohyphal differentiation in yeast. Proc Natl Acad Sci U S A 93(16):8419-24 SGD PMID 8710886
  3. Jump up ↑ Rupp S, et al. (1999) MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene. EMBO J 18(5):1257-69 SGD PMID 10064592
  4. ↑ Jump up to: 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 SGD PMID 12556493
  5. ↑ Jump up to: 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 submitted by Valmik K. Vyas on 2003-03-27

See Help:Categories on how to add the wiki page for this gene to a Category

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YIR019C&oldid=18651"