Difference between revisions of "YER169W"
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| − | '''Description of YER169W:''' JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway<ref name='S000121953'>Klose RJ, et al. (2007) Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol () {{SGDpaper|S000121953}} PMID 17371840</ref><ref name='S000121921'>Tu S, et al. (2007) Identification of | + | '''Description of YER169W:''' JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway<ref name='S000121953'>Klose RJ, et al. (2007) Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol () {{SGDpaper|S000121953}} PMID 17371840</ref><ref name='S000121921'>Tu S, et al. (2007) Identification of Histone Demethylases in Saccharomyces cerevisiae. J Biol Chem 282(19):14262-71 {{SGDpaper|S000121921}} PMID 17369256</ref><ref name='S000069126'>Kim EM, et al. (2002) Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res 30(3):643-8 {{SGDpaper|S000069126}} PMID 11809875</ref><ref name='S000046845'>Jang YK, et al. (1999) RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol 19(11):7630-8 |
{{SGDpaper|S000046845}} PMID 10523651</ref> | {{SGDpaper|S000046845}} PMID 10523651</ref> | ||
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Revision as of 13:05, 12 May 2007
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| Systematic name | YER169W |
| Gene name | RPH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:523364..525754 |
| Primary SGDID | S000000971 |
Description of YER169W: JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway[1][2][3][4]
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References
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- ↑ Klose RJ, et al. (2007) Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol () SGD PMID 17371840
- ↑ Tu S, et al. (2007) Identification of Histone Demethylases in Saccharomyces cerevisiae. J Biol Chem 282(19):14262-71 SGD PMID 17369256
- ↑ Kim EM, et al. (2002) Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res 30(3):643-8 SGD PMID 11809875
- ↑ Jang YK, et al. (1999) RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol 19(11):7630-8 SGD PMID 10523651
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