Difference between revisions of "YGR280C"
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|nowrap| Chr VII:1051731..1050916 | |nowrap| Chr VII:1051731..1050916 | ||
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 07:17, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR280C |
| Gene name | PXR1 |
| Aliases | GNO1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:1051731..1050916 |
Description of YGR280C: Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain[1][2][3]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Lin J and Blackburn EH (2004) Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA. Genes Dev 18(4):387-96 SGD PMID 14977919
- ↑ Guglielmi B and Werner M (2002) The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition. J Biol Chem 277(38):35712-9 SGD PMID 12107183
- ↑ Zhou XZ and Lu KP (2001) The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. Cell 107(3):347-59 SGD PMID 11701125
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