Difference between revisions of "YGL037C"

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==Community Commentary==
 
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==References==
 
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Revision as of 07:17, 30 January 2007

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Systematic name YGL037C
Gene name PNC1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:427953..427303


Description of YGL037C: Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span[1][2]




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Community Commentary

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References

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  1. Anderson RM, et al. (2003) Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936):181-5 SGD PMID 12736687
  2. Ghislain M, et al. (2002) Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1. Yeast 19(3):215-24 SGD PMID 11816029

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