Difference between revisions of "YFR010W"
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|nowrap| Chr VI:165060..166559 | |nowrap| Chr VI:165060..166559 | ||
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 07:17, 30 January 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YFR010W |
Gene name | UBP6 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VI:165060..166559 |
Description of YFR010W: Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds[1][2][3][4]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Chernova TA, et al. (2003) Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool. J Biol Chem 278(52):52102-15 SGD PMID 14559899
- ↑ Hanna J, et al. (2003) Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol Cell Biol 23(24):9251-61 SGD PMID 14645527
- ↑ Guterman A and Glickman MH (2004) Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. J Biol Chem 279(3):1729-38 SGD PMID 14581483
- ↑ Park KC, et al. (1997) Purification and characterization of UBP6, a new ubiquitin-specific protease in Saccharomyces cerevisiae. Arch Biochem Biophys 347(1):78-84 SGD PMID 9344467
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