Difference between revisions of "YPL123C"
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| − | '''Description of YPL123C:''' | + | '''Description of YPL123C:''' Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity<ref name='S000059474'>MacIntosh GC, et al. (2001) Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes? Proc Natl Acad Sci U S A 98(3):1018-23 {{SGDpaper|S000059474}} PMID 11158587</ref><ref name='S000129797'>Thompson DM and Parker R (2009) The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J Cell Biol |
| − | {{SGDpaper| | + | {{SGDpaper|S000129797}} PMID 19332891</ref> |
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Revision as of 13:05, 8 April 2009
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| Systematic name | YPL123C |
| Gene name | RNY1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:318944..317640 |
| Primary SGDID | S000006044 |
Description of YPL123C: Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity[1][2]
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References
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- ↑ MacIntosh GC, et al. (2001) Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes? Proc Natl Acad Sci U S A 98(3):1018-23 SGD PMID 11158587
- ↑ Thompson DM and Parker R (2009) The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae. J Cell Biol SGD PMID 19332891
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