Difference between revisions of "YOR163W"

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'''Description of YOR163W:''' Diadenosine polyphosphate hydrolase, member of the MutT family of nucleotide hydrolases with high specificity for diadenosine hexa- and pentaphosphates, required for efficient hydrolysis of diphosphorylated inositol polyphosphates<ref name='S000046998'>Safrany ST, et al. (1999) The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein. J Biol Chem 274(31):21735-40 {{SGDpaper|S000046998}} PMID 10419486</ref><ref name='S000039733'>Cartwright JL and McLennan AG (1999) The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5&quot;'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family. J Biol Chem 274(13):8604-10
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'''Description of YOR163W:''' Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases<ref name='S000046998'>Safrany ST, et al. (1999) The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein. J Biol Chem 274(31):21735-40 {{SGDpaper|S000046998}} PMID 10419486</ref><ref name='S000039733'>Cartwright JL and McLennan AG (1999) The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5&quot;'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family. J Biol Chem 274(13):8604-10
 
  {{SGDpaper|S000039733}} PMID 10085096</ref>
 
  {{SGDpaper|S000039733}} PMID 10085096</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YOR163W
Gene name DDP1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:642742..643308
Primary SGDID S000005689


Description of YOR163W: Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [3] [4]





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References

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  1. Safrany ST, et al. (1999) The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein. J Biol Chem 274(31):21735-40 SGD PMID 10419486
  2. Cartwright JL and McLennan AG (1999) The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family. J Biol Chem 274(13):8604-10 SGD PMID 10085096
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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